{"id":398,"date":"2024-11-07T08:19:12","date_gmt":"2024-11-07T08:19:12","guid":{"rendered":"https:\/\/en.hengkangpharm.cn\/?p=398"},"modified":"2025-02-21T02:42:00","modified_gmt":"2025-02-21T02:42:00","slug":"mesalazine_mesalamine","status":"publish","type":"post","link":"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/","title":{"rendered":"Mesalazine\/Mesalamine API"},"content":{"rendered":"\n<p class=\"has-text-align-center has-ast-global-color-1-background-color has-background\">Mesalazine\/Mesalamine API<\/p>\n\n\n\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"border-style:none;border-width:0px;flex-basis:70%\">\n<figure class=\"wp-block-image aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"214\" height=\"138\" src=\"https:\/\/en.hengkangpharm.cn\/wp-content\/uploads\/2024\/11\/\u7f8e\u6c99\u62c9\u55ea89-57-6.gif\" alt=\"\" class=\"wp-image-409\"\/><figcaption class=\"wp-element-caption\">Chemical Structure<\/figcaption><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column has-medium-font-size is-layout-flow wp-container-core-column-is-layout-fd134cff wp-block-column-is-layout-flow\" style=\"border-style:none;border-width:0px;padding-right:0;padding-left:0;flex-basis:50%\"><ul class=\"wp-block-categories-list alignright wp-block-categories\">\t<li class=\"cat-item cat-item-6\"><a href=\"https:\/\/en.hengkangpharm.cn\/index.php\/category\/apis\/\">APIs<\/a>\n<\/li>\n\t<li class=\"cat-item cat-item-17\"><a href=\"https:\/\/en.hengkangpharm.cn\/index.php\/category\/excipient\/\">Excipient<\/a>\n<\/li>\n\t<li class=\"cat-item cat-item-21\"><a href=\"https:\/\/en.hengkangpharm.cn\/index.php\/category\/fdfs\/\">FDFs<\/a>\n<\/li>\n\t<li class=\"cat-item cat-item-20\"><a 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Nucleoside<\/a>\n<\/li>\n\t<li class=\"cat-item cat-item-16\"><a href=\"https:\/\/en.hengkangpharm.cn\/index.php\/category\/nucleoside\/protected-nucleoside\/\">Protected Nucleoside<\/a>\n<\/li>\n<\/ul>\n<\/li>\n\t<li class=\"cat-item cat-item-8\"><a href=\"https:\/\/en.hengkangpharm.cn\/index.php\/category\/phosphoramidites\/\">Phosphoramidites<\/a>\n<ul class='children'>\n\t<li class=\"cat-item cat-item-12\"><a href=\"https:\/\/en.hengkangpharm.cn\/index.php\/category\/phosphoramidites\/2-fluoro-phosphoramidites\/\">2&#039;-Fluoro Phosphoramidites<\/a>\n<\/li>\n\t<li class=\"cat-item cat-item-11\"><a href=\"https:\/\/en.hengkangpharm.cn\/index.php\/category\/phosphoramidites\/2-o-me-phosphoramidites\/\">2&#039;-O-Me Phosphoramidites<\/a>\n<\/li>\n\t<li class=\"cat-item cat-item-9\"><a href=\"https:\/\/en.hengkangpharm.cn\/index.php\/category\/phosphoramidites\/dna-phosphoramidites\/\">DNA Phosphoramidites<\/a>\n<\/li>\n\t<li class=\"cat-item cat-item-10\"><a href=\"https:\/\/en.hengkangpharm.cn\/index.php\/category\/phosphoramidites\/tbdms-phosphoramidites\/\">TBDMS Phosphoramidites<\/a>\n<\/li>\n<\/ul>\n<\/li>\n\t<li class=\"cat-item cat-item-1\"><a href=\"https:\/\/en.hengkangpharm.cn\/index.php\/category\/uncategorized\/\">Uncategorized<\/a>\n<\/li>\n<\/ul><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:75%\">\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Product Name<\/td><td>Mesalazine\/Mesalamine<\/td><\/tr><tr><td>CAS NO.<\/td><td>89-57-6<\/td><\/tr><tr><td>Chemical Name<\/td><td>5-Aminosalicylic acid<\/td><\/tr><tr><td>Quanlity standard<\/td><td>EP\uff0cUSP\uff0cJP<\/td><\/tr><tr><td>Application\/Indication<\/td><td>Ulcerative Colitis\/Crohn&#8217;s<\/td><\/tr><tr><td>Item No.<\/td><td><\/td><\/tr><tr><td>Note<\/td><td>Hengkang Pharm is approved US FDA, EU EDQM, JP PMDA manufacturer in China.<\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Packing size<\/td><td>25kg\/drum<\/td><\/tr><tr><td>Storage condition<\/td><td>In an airtight container, protected from light<\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div>\n<\/div>\n\n\n\n<p class=\"has-text-align-left\">CEP\/USFDA\/EU GMP\/COPP\/WC; US DMF#: 0373195<\/p>\n\n\n\n<p class=\"has-text-align-left\">Synonym: Aminosalicylic acid, 98.5%, IKK inhibitor;2-HYDROXY-5-AMINOBENZOIC ACID;3-Carboxy-4-hydroxyaniline;5-AMINO-2-HYDROXYBENZOIC ACID;5-AMINOSALICYLIC ACID;5-ASA;5-AS;rowasa<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mesalazine\/Mesalamine API Product Name Mesalazine\/Mesalamine CAS NO. 89-57-6 Chemical Name 5-Aminosalicylic acid Quanlity standard EP\uff0cUSP\uff0cJP Application\/Indication Ulcerative Colitis\/Crohn&#8217;s Item No. Note Hengkang Pharm is approved US FDA, EU EDQM, JP PMDA manufacturer in China. Packing size 25kg\/drum Storage condition In an airtight container, protected from light CEP\/USFDA\/EU GMP\/COPP\/WC; US DMF#: 0373195 Synonym: Aminosalicylic acid, 98.5%, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[6],"tags":[],"class_list":["post-398","post","type-post","status-publish","format-standard","hentry","category-apis"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Mesalazine\/Mesalamine API - Zhejiang Hengkang Pharmaceutical<\/title>\n<meta name=\"description\" content=\"Mesalamine (USAN), also known as 5-aminosalicylic acid (5-ASA), is primarily indicated to treat inflammatory bowel disease and is effective in inducing or maintaining remission in mild-to-moderate cases of ulcerative colitis. Topical mesalamine stands as the first-line treatment for this condition. Clinicians may use 5-ASA off-label in Crohn disease following surgical resection of the affected bowel. Although patients with ulcerative colitis typically receive 5-ASA prescriptions from their managing gastroenterologist or primary care clinician, a surgeon may become involved in off-label uses. This activity provides healthcare professionals with a comprehensive understanding of mesalamine, covering FDA-approved indications, mechanisms of action, administration strategies, contraindications, and adverse effects profile. This activity also highlights the crucial role of the interprofessional healthcare team in effectively treating patients with ulcerative colitis, inflammatory bowel disease, and related conditions by enhancing their understanding of mesalamine&#039;s indications. Oral mesalazine (also known as mesalamine) is a 5-aminosalicylic acid compound used in the treatment of mild to moderate ulcerative colitis, with high rates of efficacy in induction and maintenance of remission. The therapeutic effect of mesalazine occurs topically at the site of diseased colonic mucosa. A myriad of oral mesalazine preparations have been formulated with various drug delivery methods to minimize systemic absorption and maximise drug availability at the inflamed colonic epithelium. It remains unclear whether different oral mesalazine formulations are bioequivalent. 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Clinicians may use 5-ASA off-label in Crohn disease following surgical resection of the affected bowel. Although patients with ulcerative colitis typically receive 5-ASA prescriptions from their managing gastroenterologist or primary care clinician, a surgeon may become involved in off-label uses. This activity provides healthcare professionals with a comprehensive understanding of mesalamine, covering FDA-approved indications, mechanisms of action, administration strategies, contraindications, and adverse effects profile. This activity also highlights the crucial role of the interprofessional healthcare team in effectively treating patients with ulcerative colitis, inflammatory bowel disease, and related conditions by enhancing their understanding of mesalamine&#039;s indications. Oral mesalazine (also known as mesalamine) is a 5-aminosalicylic acid compound used in the treatment of mild to moderate ulcerative colitis, with high rates of efficacy in induction and maintenance of remission. The therapeutic effect of mesalazine occurs topically at the site of diseased colonic mucosa. A myriad of oral mesalazine preparations have been formulated with various drug delivery methods to minimize systemic absorption and maximise drug availability at the inflamed colonic epithelium. It remains unclear whether different oral mesalazine formulations are bioequivalent. This review aims to evaluate the differences between mesalazine formulations based on the currently available literature and explore factors which may influence the selection of one agent above another.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/\" \/>\n<meta property=\"og:site_name\" content=\"Zhejiang Hengkang Pharmaceutical\" \/>\n<meta property=\"article:published_time\" content=\"2024-11-07T08:19:12+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-02-21T02:42:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/en.hengkangpharm.cn\/wp-content\/uploads\/2024\/01\/\u84dd\u8272\u7eff\u8272\u5206\u5b50banner1-2.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1175\" \/>\n\t<meta property=\"og:image:height\" content=\"200\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"HengkangPharm\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"HengkangPharm\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/\"},\"author\":{\"name\":\"HengkangPharm\",\"@id\":\"https:\/\/en.hengkangpharm.cn\/#\/schema\/person\/18ab6fcb8d86ccabdfd1e2d466afaac4\"},\"headline\":\"Mesalazine\/Mesalamine API\",\"datePublished\":\"2024-11-07T08:19:12+00:00\",\"dateModified\":\"2025-02-21T02:42:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/\"},\"wordCount\":86,\"publisher\":{\"@id\":\"https:\/\/en.hengkangpharm.cn\/#organization\"},\"articleSection\":[\"APIs\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/\",\"url\":\"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/\",\"name\":\"Mesalazine\/Mesalamine API - Zhejiang Hengkang Pharmaceutical\",\"isPartOf\":{\"@id\":\"https:\/\/en.hengkangpharm.cn\/#website\"},\"datePublished\":\"2024-11-07T08:19:12+00:00\",\"dateModified\":\"2025-02-21T02:42:00+00:00\",\"description\":\"Mesalamine (USAN), also known as 5-aminosalicylic acid (5-ASA), is primarily indicated to treat inflammatory bowel disease and is effective in inducing or maintaining remission in mild-to-moderate cases of ulcerative colitis. Topical mesalamine stands as the first-line treatment for this condition. Clinicians may use 5-ASA off-label in Crohn disease following surgical resection of the affected bowel. Although patients with ulcerative colitis typically receive 5-ASA prescriptions from their managing gastroenterologist or primary care clinician, a surgeon may become involved in off-label uses. This activity provides healthcare professionals with a comprehensive understanding of mesalamine, covering FDA-approved indications, mechanisms of action, administration strategies, contraindications, and adverse effects profile. This activity also highlights the crucial role of the interprofessional healthcare team in effectively treating patients with ulcerative colitis, inflammatory bowel disease, and related conditions by enhancing their understanding of mesalamine's indications. Oral mesalazine (also known as mesalamine) is a 5-aminosalicylic acid compound used in the treatment of mild to moderate ulcerative colitis, with high rates of efficacy in induction and maintenance of remission. The therapeutic effect of mesalazine occurs topically at the site of diseased colonic mucosa. A myriad of oral mesalazine preparations have been formulated with various drug delivery methods to minimize systemic absorption and maximise drug availability at the inflamed colonic epithelium. It remains unclear whether different oral mesalazine formulations are bioequivalent. This review aims to evaluate the differences between mesalazine formulations based on the currently available literature and explore factors which may influence the selection of one agent above another.\",\"breadcrumb\":{\"@id\":\"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/en.hengkangpharm.cn\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Mesalazine\/Mesalamine API\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/en.hengkangpharm.cn\/#website\",\"url\":\"https:\/\/en.hengkangpharm.cn\/\",\"name\":\"Zhejiang Hengkang Pharmaceutical\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/en.hengkangpharm.cn\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/en.hengkangpharm.cn\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/en.hengkangpharm.cn\/#organization\",\"name\":\"Zhejiang Hengkang Pharmaceutical\",\"url\":\"https:\/\/en.hengkangpharm.cn\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/en.hengkangpharm.cn\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/en.hengkangpharm.cn\/wp-content\/uploads\/2024\/01\/cropped-\u6052\u5eb7-logo-\u7f51\u7ad9200-80px\u526f\u672c-2.png\",\"contentUrl\":\"https:\/\/en.hengkangpharm.cn\/wp-content\/uploads\/2024\/01\/cropped-\u6052\u5eb7-logo-\u7f51\u7ad9200-80px\u526f\u672c-2.png\",\"width\":200,\"height\":67,\"caption\":\"Zhejiang Hengkang Pharmaceutical\"},\"image\":{\"@id\":\"https:\/\/en.hengkangpharm.cn\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.linkedin.com\/company\/zhejiang-hengkang-pharmaceutical-co-ltd\/mycompany\/verification\/?viewAsMember=true\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/en.hengkangpharm.cn\/#\/schema\/person\/18ab6fcb8d86ccabdfd1e2d466afaac4\",\"name\":\"HengkangPharm\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/en.hengkangpharm.cn\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/38c8fe2e7a9f2d5ff6b0d936418c48f5b3dfa8b5ed79e72cde2d23175b740122?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/38c8fe2e7a9f2d5ff6b0d936418c48f5b3dfa8b5ed79e72cde2d23175b740122?s=96&d=mm&r=g\",\"caption\":\"HengkangPharm\"},\"sameAs\":[\"http:\/\/en.hengkangpharm.cn\"],\"url\":\"https:\/\/en.hengkangpharm.cn\/index.php\/author\/admin\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Mesalazine\/Mesalamine API - Zhejiang Hengkang Pharmaceutical","description":"Mesalamine (USAN), also known as 5-aminosalicylic acid (5-ASA), is primarily indicated to treat inflammatory bowel disease and is effective in inducing or maintaining remission in mild-to-moderate cases of ulcerative colitis. 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Oral mesalazine (also known as mesalamine) is a 5-aminosalicylic acid compound used in the treatment of mild to moderate ulcerative colitis, with high rates of efficacy in induction and maintenance of remission. The therapeutic effect of mesalazine occurs topically at the site of diseased colonic mucosa. A myriad of oral mesalazine preparations have been formulated with various drug delivery methods to minimize systemic absorption and maximise drug availability at the inflamed colonic epithelium. It remains unclear whether different oral mesalazine formulations are bioequivalent. 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A myriad of oral mesalazine preparations have been formulated with various drug delivery methods to minimize systemic absorption and maximise drug availability at the inflamed colonic epithelium. It remains unclear whether different oral mesalazine formulations are bioequivalent. This review aims to evaluate the differences between mesalazine formulations based on the currently available literature and explore factors which may influence the selection of one agent above another.","og_url":"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/","og_site_name":"Zhejiang Hengkang Pharmaceutical","article_published_time":"2024-11-07T08:19:12+00:00","article_modified_time":"2025-02-21T02:42:00+00:00","og_image":[{"width":1175,"height":200,"url":"https:\/\/en.hengkangpharm.cn\/wp-content\/uploads\/2024\/01\/\u84dd\u8272\u7eff\u8272\u5206\u5b50banner1-2.png","type":"image\/png"}],"author":"HengkangPharm","twitter_card":"summary_large_image","twitter_misc":{"Written by":"HengkangPharm","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/#article","isPartOf":{"@id":"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/"},"author":{"name":"HengkangPharm","@id":"https:\/\/en.hengkangpharm.cn\/#\/schema\/person\/18ab6fcb8d86ccabdfd1e2d466afaac4"},"headline":"Mesalazine\/Mesalamine API","datePublished":"2024-11-07T08:19:12+00:00","dateModified":"2025-02-21T02:42:00+00:00","mainEntityOfPage":{"@id":"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/"},"wordCount":86,"publisher":{"@id":"https:\/\/en.hengkangpharm.cn\/#organization"},"articleSection":["APIs"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/","url":"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/","name":"Mesalazine\/Mesalamine API - Zhejiang Hengkang Pharmaceutical","isPartOf":{"@id":"https:\/\/en.hengkangpharm.cn\/#website"},"datePublished":"2024-11-07T08:19:12+00:00","dateModified":"2025-02-21T02:42:00+00:00","description":"Mesalamine (USAN), also known as 5-aminosalicylic acid (5-ASA), is primarily indicated to treat inflammatory bowel disease and is effective in inducing or maintaining remission in mild-to-moderate cases of ulcerative colitis. Topical mesalamine stands as the first-line treatment for this condition. Clinicians may use 5-ASA off-label in Crohn disease following surgical resection of the affected bowel. Although patients with ulcerative colitis typically receive 5-ASA prescriptions from their managing gastroenterologist or primary care clinician, a surgeon may become involved in off-label uses. This activity provides healthcare professionals with a comprehensive understanding of mesalamine, covering FDA-approved indications, mechanisms of action, administration strategies, contraindications, and adverse effects profile. This activity also highlights the crucial role of the interprofessional healthcare team in effectively treating patients with ulcerative colitis, inflammatory bowel disease, and related conditions by enhancing their understanding of mesalamine's indications. Oral mesalazine (also known as mesalamine) is a 5-aminosalicylic acid compound used in the treatment of mild to moderate ulcerative colitis, with high rates of efficacy in induction and maintenance of remission. The therapeutic effect of mesalazine occurs topically at the site of diseased colonic mucosa. A myriad of oral mesalazine preparations have been formulated with various drug delivery methods to minimize systemic absorption and maximise drug availability at the inflamed colonic epithelium. It remains unclear whether different oral mesalazine formulations are bioequivalent. This review aims to evaluate the differences between mesalazine formulations based on the currently available literature and explore factors which may influence the selection of one agent above another.","breadcrumb":{"@id":"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/en.hengkangpharm.cn\/index.php\/apis\/mesalazine_mesalamine\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/en.hengkangpharm.cn\/"},{"@type":"ListItem","position":2,"name":"Mesalazine\/Mesalamine API"}]},{"@type":"WebSite","@id":"https:\/\/en.hengkangpharm.cn\/#website","url":"https:\/\/en.hengkangpharm.cn\/","name":"Zhejiang Hengkang Pharmaceutical","description":"","publisher":{"@id":"https:\/\/en.hengkangpharm.cn\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/en.hengkangpharm.cn\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/en.hengkangpharm.cn\/#organization","name":"Zhejiang Hengkang Pharmaceutical","url":"https:\/\/en.hengkangpharm.cn\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/en.hengkangpharm.cn\/#\/schema\/logo\/image\/","url":"https:\/\/en.hengkangpharm.cn\/wp-content\/uploads\/2024\/01\/cropped-\u6052\u5eb7-logo-\u7f51\u7ad9200-80px\u526f\u672c-2.png","contentUrl":"https:\/\/en.hengkangpharm.cn\/wp-content\/uploads\/2024\/01\/cropped-\u6052\u5eb7-logo-\u7f51\u7ad9200-80px\u526f\u672c-2.png","width":200,"height":67,"caption":"Zhejiang Hengkang Pharmaceutical"},"image":{"@id":"https:\/\/en.hengkangpharm.cn\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.linkedin.com\/company\/zhejiang-hengkang-pharmaceutical-co-ltd\/mycompany\/verification\/?viewAsMember=true"]},{"@type":"Person","@id":"https:\/\/en.hengkangpharm.cn\/#\/schema\/person\/18ab6fcb8d86ccabdfd1e2d466afaac4","name":"HengkangPharm","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/en.hengkangpharm.cn\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/38c8fe2e7a9f2d5ff6b0d936418c48f5b3dfa8b5ed79e72cde2d23175b740122?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/38c8fe2e7a9f2d5ff6b0d936418c48f5b3dfa8b5ed79e72cde2d23175b740122?s=96&d=mm&r=g","caption":"HengkangPharm"},"sameAs":["http:\/\/en.hengkangpharm.cn"],"url":"https:\/\/en.hengkangpharm.cn\/index.php\/author\/admin\/"}]}},"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"HengkangPharm","author_link":"https:\/\/en.hengkangpharm.cn\/index.php\/author\/admin\/"},"uagb_comment_info":0,"uagb_excerpt":"Mesalazine\/Mesalamine API Product Name Mesalazine\/Mesalamine CAS NO. 89-57-6 Chemical Name 5-Aminosalicylic acid Quanlity standard EP\uff0cUSP\uff0cJP Application\/Indication Ulcerative Colitis\/Crohn&#8217;s Item No. Note Hengkang Pharm is approved US FDA, EU EDQM, JP PMDA manufacturer in China. Packing size 25kg\/drum Storage condition In an airtight container, protected from light CEP\/USFDA\/EU GMP\/COPP\/WC; US DMF#: 0373195 Synonym: Aminosalicylic acid, 98.5%,&hellip;","_links":{"self":[{"href":"https:\/\/en.hengkangpharm.cn\/index.php\/wp-json\/wp\/v2\/posts\/398","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/en.hengkangpharm.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/en.hengkangpharm.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/en.hengkangpharm.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/en.hengkangpharm.cn\/index.php\/wp-json\/wp\/v2\/comments?post=398"}],"version-history":[{"count":4,"href":"https:\/\/en.hengkangpharm.cn\/index.php\/wp-json\/wp\/v2\/posts\/398\/revisions"}],"predecessor-version":[{"id":415,"href":"https:\/\/en.hengkangpharm.cn\/index.php\/wp-json\/wp\/v2\/posts\/398\/revisions\/415"}],"wp:attachment":[{"href":"https:\/\/en.hengkangpharm.cn\/index.php\/wp-json\/wp\/v2\/media?parent=398"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/en.hengkangpharm.cn\/index.php\/wp-json\/wp\/v2\/categories?post=398"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/en.hengkangpharm.cn\/index.php\/wp-json\/wp\/v2\/tags?post=398"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}