1.0Zhejiang Hengkang Pharmaceuticalhttps://en.hengkangpharm.cnHengkangPharmhttps://en.hengkangpharm.cn/index.php/author/admin/4-Pyrimidinamine, 5-(4-bromophenyl)-6-chloro- Zhejiang Hengkang Pharmaceuticalrich600338<blockquote class="wp-embedded-content" data-secret="gnB5Jq56WY"><a href="https://en.hengkangpharm.cn/index.php/intermediates/macitentanintermediate_2211057-81-5/">4-Pyrimidinamine, 5-(4-bromophenyl)-6-chloro-</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://en.hengkangpharm.cn/index.php/intermediates/macitentanintermediate_2211057-81-5/embed/#?secret=gnB5Jq56WY" width="600" height="338" title="“4-Pyrimidinamine, 5-(4-bromophenyl)-6-chloro-” — Zhejiang Hengkang Pharmaceutical" data-secret="gnB5Jq56WY" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script>
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4-Pyrimidinamine, 5-(4-bromophenyl)-6-chloro- is mainly used as a pharmaceutical intermediate and is an intermediate for the synthesis of Macitentan. Macitentan is an orally active endothelin ETA and ETB receptor antagonist that can block endothelin induced vasoconstriction in the trachea and large arteries.https://en.hengkangpharm.cn/wp-content/uploads/2025/02/image-80.png193151