1.0Zhejiang Hengkang Pharmaceuticalhttps://en.hengkangpharm.cnHengkangPharmhttps://en.hengkangpharm.cn/index.php/author/admin/(3,5-dichloro-4-methoxyphenyl)-(1,1-dioxo-2H-1,3-benzothiazol-3-yl)methanone - Zhejiang Hengkang Pharmaceuticalrich600338<blockquote class="wp-embedded-content" data-secret="qEMIZs9FOg"><a href="https://en.hengkangpharm.cn/index.php/intermediates/dotinuradintermediate_1285573-44-5/">(3,5-dichloro-4-methoxyphenyl)-(1,1-dioxo-2H-1,3-benzothiazol-3-yl)methanone</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://en.hengkangpharm.cn/index.php/intermediates/dotinuradintermediate_1285573-44-5/embed/#?secret=qEMIZs9FOg" width="600" height="338" title="“(3,5-dichloro-4-methoxyphenyl)-(1,1-dioxo-2H-1,3-benzothiazol-3-yl)methanone” — Zhejiang Hengkang Pharmaceutical" data-secret="qEMIZs9FOg" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script>
/*! This file is auto-generated */
!function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document);
//# sourceURL=https://en.hengkangpharm.cn/wp-includes/js/wp-embed.min.js
</script>
(3,5-dichloro-4-methoxyphenyl)-(1,1-dioxo-2H-1,3-benzothiazol-3-yl)methanone is one of the intermediates of Dotinurad, a selective URAT1 inhibitor with an IC50 of 37.2 nM. It has significant inhibitory activity on uric acid uptake and URAT1 mediated uric acid transport in primary human renal proximal tubular epithelial cells (RPTECs).https://en.hengkangpharm.cn/wp-content/uploads/2025/02/image-57.png242126