Intermediates

Phenylmethyl (3R,4S)-3-[2-[[(1,1-dimethylethoxy)carbonyl][5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]amino]acetyl]-4-ethyl-1-pyrrolidinecarboxylate Product Name:Phenylmethyl (3R,4S)-3-[2-[[(1,1-dimethylethoxy)carbonyl][5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]amino]acetyl]-4-ethyl-1-pyrrolidinecarboxylate Chemical Name:Phenylmethyl (3R,4S)-3-[2-[[(1,1-dimethylethoxy)carbonyl][5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]amino]acetyl]-4-ethyl-1-pyrrolidinecarboxylate CAS NO.:1428243-27-9 Mol. Formula:C34H39N5O7S Mol. Weight:661.77 Final API:Upadacitinib Purity or Assay:＞99% *All our products under patent are for R&D Synonym: 1-Pyrrolidinecarboxylicacid,3-[2-[[(1,1-dimethylethoxy)carbonyl][5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]amino]acetyl]-4-ethyl-,phenylmethylester,(3R,4S)-;UpadacitinibImpurity4;benzyl(3R,4S)-3-(N-(tert-butoxycarbonyl)-N-(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)glycyl)-4-ethylpyrrolidine-1-carboxylate;benzyl(3R,4S)-3-(bis(5-tosyl-5H-pyChemicalbookrrolo[2,3-b]pyrazin-2-yl)glycyl)-4-ethylpyrrolidine-1-carboxylate;(3R,4S)-3-(2-Bromoacetyl)-4-ethyl-1-pyrrolidinecarboxylicacidphenylmethylester;UpadacitinibImpurity01;Phenylmethyl(3R,4S)-3-[2-[[(1,1-dimethylethoxy)carbonyl][5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]amino]acetyl]-4-ethyl-1-pyrrolidinecarboxylate;UpadacitinibImpurity35

Upadacitinib N-1 Product Name:Upadacitinib N-1 Chemical Name:8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride (1:2) CAS NO.:2050038-84-9 Mol. Formula:C14H17N5 Mol. Weight:255.33 Final API:Upadacitinib Purity or Assay:＞99% *All our products under patent are for R&D Synonym: 3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine;8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazinehydrochloride(1:2);8-((3R,4S)-4-ethylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazineHydrochloride;12-[(3R,4S)-4-ethylpyrrolidin-3-yl]-1,5,7,10-tetrazatricyclo[7.3.0.02,6]dodChemicalbookeca-2(6),3,7,9,11-pentaene;8-((3R,4S)-4-ethylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazinedihydrochloride;8-((3R,4S)-4-ethylpyrrolidin-3-yl)-3Himidazolo[1,2-a]pyrrolino[2,3-e]pyrazinehydrochloride;3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine,8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-,hydrochloride

1-(4-aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one Product Name:1-(4-aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one Chemical Name:1-(4-aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one CAS NO.:1267610-26-3 Mol. Formula:C15H19N3O2 Mol. Weight:273.34 Final API:Apixaban Purity or Assay:＞99% *All our products under patent are for R&D Synonym: 1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone;1-(4-aMinophenyl)-3-Morpholino-5,6-dihydropyridin-2(1H)-one;2(1H)-Pyridinone,1-Chemicalbook(4-aMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-;ApixabainretMediateA;ApixabanImpurityS;ApixabanImpurity47;ApixabanintA;Apixabanrelatedimpurities2

3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one Product Name:3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one Chemical Name:3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one CAS NO.:545445-44-1 Mol. Formula:C20H25N3O3 Mol. Weight:355.44 Final API:Apixaban Purity or Assay:＞99% *All our products under patent are for R&D Synonym: 5-morpholin-4-yl-1-[4-(2-oxopiperidin-1-yl)phenyl]-2,3-dihydropyridin-6-one;3-Morpholino-1-[4-(2-oxo-1-piperidyl)phenyl]-5,6-dihydropyridin-2(1H)-one;3-Morpholino-1-(4-(Chemicalbook2-oxopiperidin-1-yl);HSK00001094;ApixabanImpurityH;ApixabanIntermediates;ApixabanImpurityP;3-Morpholin-4-yl-1-[4-(2-oxopiperidin-1-yl)phenyl]-5,6-dihydro-1H-pyridin-2-one

Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Product Name:ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Chemical Name:ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate CAS NO.:503614-91-3 Mol. Formula:C27H28N4O5 Mol. Weight:488.54 Final API:Apixaban Purity or Assay:＞99% *All our products under patent are for R&D Synonym: ethyl 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate;APIXABAN V;1-(4-methoxy-phenyl)-7-oxo-6-[4-(2-oxo-piperidin-1-yl)-phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester

(2R)-2-Hydroxy-N-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide Product Name:(2R)-2-Hydroxy-N-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide Chemical Name:(2R)-2-Hydroxy-N-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide CAS NO.:521284-19-5 Mol. Formula:C16H16N2O4 Mol. Weight:300.31 Final API:Mirabegron Purity or Assay:＞99% *All our products under patent are for R&D Synonym: alphaR)-alpha-Hydroxy-N-[2-(4-nitrophenyl)ethyl]benzeneacetamide;BenzeneacetaMide,a-hydroxy-N-[2-(4-nitrophenyl)ethyl]-,(aR)-;BenzeneacetaMide,-hydroxy-N-[2-(4-nitrophenyl)ethyl]-,(R)-;R-a-hydroxy-N-[2-(4-nitroChemicalbookphenyl)ethyl]-BenzeneacetaMide;(R)-N-(4-nitrophenethyl)-2-hydroxy-2-phenylacetamide;(R)-2-Hydroxy-N-(4-nitrophenethyl)-2-phenylacetamide;MirabegronINT1;(R)-2-hydroxy-N-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide

(1R)-2-[2-(4-nitrophenyl)ethylamino]-1-phenylethanol,hydrochloride Product Name:(1R)-2-[2-(4-nitrophenyl)ethylamino]-1-phenylethanol,hydrochloride Chemical Name:(1R)-2-[2-(4-nitrophenyl)ethylamino]-1-phenylethanol,hydrochloride CAS NO.:521284-21-9 Mol. Formula:C16H19ClN2O3 Mol. Weight:322.79 Final API:Mirabegron Purity or Assay:＞99% *All our products under patent are for R&D Synonym: (R)-2-[[2-(4-nitrophenylethyl]aMino]-1-phenylethanolMonohydrochloride;(R)-2-(4-NITROPHENETHYLAMINO)-1-PHENYLETHANOLHCL;(R)-2-(4-nitrophenyl)ethylamino)-1-phenylethanolhydrochloride?;(R)-alpha-[[(4-Nitrophenethyl)amino]methyl]benzylAlcoholHydrochloride;(alphaR)-aChemicalbooklpha-[[[2-(4-Nitrophenyl)ethyl]aMino]Methyl]benzeneMethanolhydrochloride;(R)-2-[2-(4-Nitro-phenyl)-ethylamino]-1-phenyl-ethanolHydrochloride;R-2-((4-nitrophenethyl)amino)-1-phenylethan-1-olhydrochloride;(R)-2-((4-Nitrophenethyl)aMino)-1-phenylethanolhydrochloride

(R)-2-((4-AMinophenethyl)aMino)-1-phenylethanol Product Name:(R)-2-((4-AMinophenethyl)aMino)-1-phenylethanol Chemical Name:(R)-2-((4-AMinophenethyl)aMino)-1-phenylethanol CAS NO.:391901-45-4 Mol. Formula:C16H20N2O Mol. Weight:256.35 Final API:Mirabegron Purity or Assay:＞99% *All our products under patent are for R&D Synonym: BenzeneMethanol,a-[[[2-(4-aMinophenyl)ethyl]aMino]Methyl]-,(aR)-;BenzeneMethanol,-[[[2-(4-aMinophenyl)ethyl]aMino]Methyl]-,(R)-;(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]-benzenemethanol;(R)-2-((4-AMinophChemicalbookenethyl)aMino)-1-phenylethanol;(R)-2-((4-aminophenethyl)amino)-1-phenylethan-1-ol;(1R)-2-[(4-aminophenethyl)amino]-1-phenyl-1-ethanol;MiraBegronimpurityH;(aR)-a-[[[2-(4-Aminophenyl)ethyl]amino]methyl]-benzenemethanol

2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile Product Name:2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile Chemical Name:2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile CAS NO.:312307-38-3 Mol. Formula:C11H7FN2O Mol. Weight:202.19 Final API:Vonoprazan Purity or Assay:＞99% *All our products under patent are for R&D Synonym: Propanedinitrile, 2-[2-(2-fluorophenyl)-2-oxoethyl]-; Propanedinitrile,2-[2-(2-fluorophenyl)-2-oxoethyl]-; [2-(2-fluorophenyl)-2-oxoethyl]propanedinitrile

5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde Product Name:5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde Chemical Name:5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde CAS NO.:881674-56-2 Mol. Formula:C11H8FNO Mol. Weight:189.19 Final API:Vonopazan fumarate Purity or Assay:＞99% *All our products under patent are for R&D Synonym: 1H-Pyrrole-3-carboxaldehyde,5-(2-fluorophenyl)-;5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde;5-(2-Fluorophenyl)-1H-pyrrole-3-carbal…;5-(2-Fluorophenyl)-1H-pyrrole-3-carboxaldehyde;1H-ChemicalbookPyrrole-3-carboxaldehyde,5-(2-fluorophenyl)-1H-pyrrole-;TAK438Impurity54;1H-Pyrrole-3-carboxaldehyde,5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde;TAK-438(Vonoprazanfumarate)intermediate3

5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde Product Name:5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde Chemical Name:5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde CAS NO.:881677-11-8 Mol. Formula:C16H11FN2O3S Mol. Weight:330.33 Final API:Vonoprazan Purity or Assay:＞99% *All our products under patent are for R&D Synonym: (5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine;5-(2-Fluorophenyl)-1-[(pyridin-3-yl)sulfonyl]-1H-pyrrole-3-carboxaldehyde DMF

5-(pyridin-2-yl)-1,2-dihydropyridin-2-one Product Name:5-(pyridin-2-yl)-1,2-dihydropyridin-2-one Chemical Name:5-(pyridin-2-yl)-1,2-dihydropyridin-2-one CAS NO.:381233-78-9 Mol. Formula:C10H8N2O Mol. Weight:172.19 Final API:PeraMpanel Purity or Assay:＞99% *All our products under patent are for R&D Synonym: [2,3′-BIPYRIDIN]-6′(1’H)-ONE;5-(2-PYRIDYL)-1,2-DIHYDROPYRIDIN-2-ONE;5-(Pyridin-2-yl)-2(1H)-pyridone;5-(Pyridin-2-yl)-1,2-dihydropyrChemicalbookidin-2-one;5-(Pyridin-2-yl)pyridin-2(1H)-one;5-(2-Pyridyl)pyridin-2(1H)-one;5-pyridin-2-yl-1H-pyridin-2-one;5-(2-PYRIDYL)-2-PYRIDONE

1-phenyl-5-pyridin-2-ylpyridin-2-one Product Name:1-phenyl-5-pyridin-2-ylpyridin-2-one Chemical Name:1-phenyl-5-pyridin-2-ylpyridin-2-one CAS NO.:381725-50-4 Mol. Formula:C16H12N2O Mol. Weight:248.28 Final API:Perampanel Purity or Assay:＞99% *All our products under patent are for R&D Synonym: 1-Phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-one;1-phenyl-5-pyridin-2-ylpyridin-2-one;1′-Phenyl-[2,3′-bipyridin]-6′(1’H)-one;1-PHENYL-5-(PYRIDIN-2-YL)ChemicalbookPYRIDIN-2(1H)-ONE;[2,3′-Bipyridin]-6′(1’H)-one,1′-phenyl-;PerampanelImpurity4;PerampanelIntermediate2;1-Phenyl-5-(pyridin-2-y1)-1,2-dihydropyridin-2-one

3-bromo-1-phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-one Product Name:3-bromo-1-phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-one Chemical Name:3-bromo-1-phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-one CAS NO.:381248-06-2 Mol. Formula:C16H11BrN2O Mol. Weight:327.18 Final API:Perampanel Purity or Assay:＞99% *All our products under patent are for R&D Synonym:5′-broMo-1′-phenyl-[2,3′-bipyridin]-6′(1’H)-one;3-BroMo-1-phenyl-5-(pyridin-2-yl)pyridin-2(1H)-one;3-Bromo-1-phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-one;3-Bromo-1-phenyl-5-(pyridin-2-yl)-2(1H)-pyridoneChemicalbook;3-Bromo-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one;3-bromo-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridine-2-one;3-bromo-1-phenyl-5-pyridin-2-ylpyridin-2-one;[2,3′-Bipyridin]-6′(1’H)-one,5′-bromo-1′-phenyl-

2-​Bromo-​4-​phenoxybenzoic acid Product Name:2-​Bromo-​4-​phenoxybenzoic acid Chemical Name:2-​Bromo-​4-​phenoxybenzoic acid CAS NO.:1237123-42-0 Mol. Formula:C13H9BrO3 Mol. Weight:293.12 Final API:Roxadustat Purity or Assay:＞99% *All our products under patent are for R&D Synonym:/

Ethyl 5-(2-bromo-4-phenoxyphenyl)oxazole-4-carboxylate Product Name:Ethyl 5-(2-bromo-4-phenoxyphenyl)oxazole-4-carboxylate Chemical Name:Ethyl 5-(2-bromo-4-phenoxyphenyl)oxazole-4-carboxylate CAS NO.:2222121-33-5 Mol. Formula:C18H14BrNO4 Mol. Weight:388.22 Final API:Roxadustat Purity or Assay:＞99% *All our products under patent are for R&D Synonym:4-Oxazolecarboxylic acid, 5-(2-bromo-4-phenoxyphenyl)-, ethyl ester

Ethyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate Product Name:Ethyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate Chemical Name:Ethyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate CAS NO.:1809286-36-9 Mol. Formula:C19H17NO4 Mol. Weight:323.35 Final API:Roxadustat Purity or Assay:＞99% *All our products under patent are for R&D Synonym: 4-hydroxy-1-methyl-7-phenoxy-3-Isoquinolinecarboxylic acid ethyl ester;3-Isoquinolinecarboxylic acid, 4-hydroxy-1-methyl-7-phenoxy-, ethyl ester;ethyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate

Benzothiazoline Product Name:benzothiazoline Chemical Name:2,3-dihydro-1,3-benzothiazole CAS NO.:4433-52-7 Mol. Formula:C7H7NS Mol. Weight:137.2 Final API:Dotinurad Purity or Assay:＞99% *All our products under patent are for R&D Synonym: 2,3-dihydro-1,3-benzothiazole;2,3-Dihydrobenzo[d]thiazole;2,3-Dihydrobenzothiazole;Benzothiazole, 2,3-dihydro-;Pyrithiobac Impurity 3

2H-1,3-benzothiazol-3-yl-(3,5-dichloro-4-methoxyphenyl)methanone Product Name:2H-1,3-benzothiazol-3-yl-(3,5-dichloro-4-methoxyphenyl)methanone Chemical Name:2H-1,3-benzothiazol-3-yl-(3,5-dichloro-4-methoxyphenyl)methanone CAS NO.:1285573-42-3 Mol. Formula:C15H11Cl2NO2S Mol. Weight:340.22 Final API:Dotinurad Purity or Assay:＞99% *All our products under patent are for R&D Synonym: Methanone,3(2H)-benzothiazolyl(3,5-dichloro-4-methoxyphenyl)-;DotinuradImpurity19;3-(3,5-dichloro-4-methoxybenzoyl)-1,2-dihydro-3H-1,3-benzothiazole;（3(2H)-Benzothiazolyl(3,5-dichloChemicalbookro-4-methoxyphenyl)methanone）;benzo[d]thiazol-3(2H)-yl(3,5-dichloro-4-methoxyphenyl)methanone;3-((3,5-dichloro-4-hydroxyphenyl)(hydroxy)methyl)-2,3-dihydrobenzo[d]thiazole1,1-dioxide

(3,5-dichloro-4-methoxyphenyl)-(1,1-dioxo-2H-1,3-benzothiazol-3-yl)methanone Product Name:(3,5-dichloro-4-methoxyphenyl)-(1,1-dioxo-2H-1,3-benzothiazol-3-yl)methanone Chemical Name:(3,5-dichloro-4-methoxyphenyl)-(1,1-dioxo-2H-1,3-benzothiazol-3-yl)methanone CAS NO.:1285573-44-5 Mol. Formula:C14H9Cl2NO4S Mol. Weight:358.19 Final API:Dotinurad Purity or Assay:＞99% *All our products under patent are for R&D Synonym: 1;Methanone,(3,5-dichloro-4-methoxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)-;3-(3,5-dichloro-4-methoxybenzoyl)-1,1-dioxo-1,2-dihydro-3H-1,3-benzothiazole;(3,5-Dichloro-4-metChemicalbookhoxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)methanone;(5,5,12,12-tetraoxidodibenzo[d,i][1,6,3,8]dithiadiazecine-7,14(6H,13H)-diyl)bis((3,5-dichloro-4-methoxyphenyl)methanone)